Dott.ssa Rosanna Cardani

Dott.ssa Rosanna Cardani

Responsabile Biobanca BioCor

Curriculum

La Dott.ssa Rosanna Cardani, PhD è attualmente la Responsabile della Biobanca BioCor.

Ha conseguito la Laurea in Biologia Cellulare e il Dottorato di Ricerca in Biologia Cellulare e Molecolare presso l’Università degli Studi di Milano dove ha lavorato come Postdoc Researcher presso il Laboratorio di Anatomia Comparata, conducendo studi sui meccanismi molecolari della cancerogenesi epatica e renale in modelli murini.

Nel 2003, ha iniziato la sua attività di ricerca sulle miopatie umane come Senior Researcher presso il Laboratorio di Malattie Neuromuscolari dell’Università degli Studi di Milano mettendo a punto un protocollo di ibridazione in situ (FISH) utilizzato come metodo diagnostico rapido della Distrofia Miotonica di Tipo 2.

Dal 2011 diventa Responsabile del Laboratorio di Istopatologia Muscolare e Biologia Molecolare presso l’IRCCS-Policlinico San Donato, focalizzando la propria ricerca sullo studio in vivo e in vitro dei meccanismi molecolari alla base di diverse malattie neuromuscolari ed in particolare delle malattie miotoniche (distrofiche e non distrofiche) a partire da biopsie di muscolo scheletrico umano.

Nel 2019 ha collaborato alla costituzione della Biobanca Cardiovascolare BioCor presso l’IRCCS-Policlinico San Donato di cui è Responsabile.

Scrivimi

Pubblicazioni

Vengono riportate solo le pubblicazioni degli ultimi 5 anni

Baci D, Tastsoglou S, Provenzano C, Perfetti A, Izzo M, Lisanti M, Frolova S, Voellenkle C, Tascini AS, Cardani R, Cardinali B, Meola G, Falcone G, Martelli F. circARHGAP10 as a candidate biomarker and therapeutic target in myotonic dystrophy type 1. Mol Ther Nucleic Acids. 2025 Jul 30;36(3):102646. doi: 10.1016/j.omtn.2025.102646. PMID: 40896579; PMCID: PMC12395532.

Russo FM, Artoni A, Cotza M, Veronese G, Cenci S, Villano M, Di Tomasso N, Pedrazzini G, Abbattista M, Novembrino C, Anguissola M, Cardani R, Peyvandi F, Ranucci M, Grasselli G. Activated Clotting Time Measured by Hemochron Signature Elite in Adult Cardiac Surgery: Implications for Clinical Practice. J Cardiothorac Vasc Anesth. 2025 Oct;39(10):2615-2622. doi: 10.1053/j.jvca.2025.05.031. Epub 2025 May 18. PMID: 40555631.

Madè A, Piella SN, Ranucci M, Gaetano C, Renna LV, Cardani R, Spinetti G, Milani V, Martelli F. LEF1-AS1 Deregulation in the Peripheral Blood of Patients with Persistent Post-COVID Symptoms. Int J Mol Sci. 2025 May 17;26(10):4806. doi: 10.3390/ijms26104806. PMID: 40429947; PMCID: PMC12112689.

Sala A, de Vincentiis C, Grimaldi F, Rubino B, Cirami M, Perillo N, Vitale R, Cardani R, Boveri S, Conti M, Spagnolo P. Can the Novel Photon-Counting CT Scan Accurately Predict Aortic Wall Thickness? Preliminary Results. Bioengineering (Basel). 2025 Mar 18;12(3):306. doi: 10.3390/bioengineering12030306. PMID: 40150770; PMCID: PMC11939590.

Castelvecchio S, Nappi R, Ramputi L, Cardani R, Mazzaccaro D, Graffigna G, Boveri S, Milani V, Baroni I, Magon A, Conte G, Trevisan MB, Cerri A, De Angeli G, Paglione G, Piepoli M, Menicanti L, Caruso R. Different patterns of lifestyles, socio-demography, clinical patterns, and cardiovascular health awareness among women. Results from the “Call for Women” population-based survey. Eur J Prev Cardiol. 2025 Mar 25:zwaf174. doi: 10.1093/eurjpc/zwaf174. Epub ahead of print. PMID: 40128943.

Curcio N, Conti M, Cardani R, Renna LV, Dell’Antonio G, Bari V, Nano G, Matrone G, Mazzaccaro D. Biomechanical assessment of vulnerable plaque: from histological evidence to ultrasound elastography and image-based computational patient-specific modelling. Front Bioeng Biotechnol. 2025 Mar 7;13:1478408. doi: 10.3389/fbioe.2025.1478408. PMID: 40124246; PMCID: PMC11925902.

Zanardo M, Ambrogi F, Asmundo L, Cardani R, Cirillo G, Colarieti A, Cozzi A, Cressoni M, Dambra I, Di Leo G, Monti CB, Nicotera L, Pomati F, Renna LV, Secchi F, Versuraro M, Vitali P, Sardanelli F. The GREENWATER study: patients’ green sensitivity and potential recovery of injected contrast agents. Eur Radiol. 2024 Oct 31. doi: 10.1007/s00330-024-11150-3. Epub ahead of print. PMID: 39480535.

Malavazos AE, Dubini C, Milani V, Boveri S, Meregalli C, Bertolini C, Buscemi C, Cardani R, Renna LV, Trevisan MB, Scravaglieri V, Cuppone MT, Menicanti L, Costa E, Ambrogi F, Ruocco C, Carruba M, Iacobellis G, Nisoli E, Corsi Romanelli MM. BNT162b2 Booster Dose Elicits a Robust Antibody Response in Subjects with Abdominal Obesity and Previous SARS-CoV-2 Infection. Vaccines (Basel). 2023 Nov 30;11(12):1796. doi: 10.3390/vaccines11121796. PMID: 38140200; PMCID: PMC10747120.

Baldassarre D, Iacoviello L, Baetta R, Roncaglioni MC, Condorelli G, Remuzzi G, Gensini G, Frati L, Ricciardi W, Conaldi PG, Uccelli A, Blandini F, Bosari S, Scambia G, Fini M, Di Malta A, Amato M, Veglia F, Bonomi A, Klersy C, Colazzo F, Pengo M, Gorini F, Auteri L, Ferrante G, Baviera M, Ambrosio G, Catapano A, Gialluisi A, Malavazos AE, Castelvecchio S, Corsi-Romanelli MM, Cardani R, La Rovere MT, Agnese V, Pane B, Prati D, Spinardi L, Liuzzo G, Arbustini E, Volterrani M, Visconti M, Werba JP, Genovese S, Bilo G, Invitti C, Di Blasio A, Lombardi C, Faini A, Rosa D, Ojeda-Fernández L, Foresta A, De Curtis A, Di Castelnuovo A, Scalvini S, Pierobon A, Gorini A, Valenti L, Luzi L, Racca A, Bandi M, Tremoli E, Menicanti L, Parati G, Pompilio G; CV-PREVITAL Study Group. Rationale and design of the CV-PREVITAL study: an Italian multiple cohort randomised controlled trial investigating innovative digital strategies in primary cardiovascular prevention. BMJ Open. 2023 Jul 14;13(7):e072040. doi: 10.1136/bmjopen-2023-072040. PMID: 37451717; PMCID: PMC10351259.

Zanardo M, Cozzi A, Cardani R, Renna LV, Pomati F, Asmundo L, Di Leo G, Sardanelli F. Reducing contrast agent residuals in hospital wastewater: the GREENWATER study protocol. Eur Radiol Exp. 2023 May 4;7(1):27. doi: 10.1186/s41747-023-00337-w. PMID: 37142839; PMCID: PMC10160294.

Renna LV, Bertani F, Podio A, Boveri S, Carrara M, Pinton A, Milani V, Spuria G, Nizza AF, Basilico S, et al (2023): Impact of BNT162b2 Booster Dose on SARS-CoV-2 Anti-Trimeric Spike Antibody Dynamics in a Large Cohort of Italian Health Care Workers. Vaccines; 11: 463.

Šušnjar U, Škrabar N, Brown AL, Abbassi Y, Phatnani H; NYGC ALS Consortium; Cortese A, Cereda C, Bugiardini E, Cardani R, Meola G, Ripolone M, Moggio M, Romano M, Secrier M, Fratta P, Buratti E. Cell environment shapes TDP-43 function with implications in neuronal and muscle disease. Commun Biol. 2022 Apr 5;5(1):314. doi: 10.1038/s42003-022-03253-8. PMID: 35383280; PMCID: PMC8983780.

Malavazos AE, Basilico S, Iacobellis G, Milani V, Cardani R, Boniardi F,Dubini C, Prandoni I, Capitanio G, Renna LV, Boveri S, Rigolini R, Carrara M, Spuria G, Cuppone T, D’acquisto A, Carpinelli L, Sacchi M, Morricone L, Secchi F, Costa E, Menicanti L, Nisoli E, Carruba M, Ambrogi F, Corsi Romanelli MM. Antibody responses to BNT162b2 mRNA vaccine: Infection-naïve individuals with abdominal obesity warrant attention. Obesity (Silver Spring). 2022 Mar;30(3):606-613. doi: 10.1002/oby.23353. Epub 2022 Feb 11. PMID: 34850576.

Mazzaccaro D, Dolci M, Perego F, Delbue S, Giannetta M, Cardani R, Valentina Renna L, Costa E, Corsi-Romanelli MM, Galli C, Pariani E, Nano G, Clemente C, Basilico N. Viral Agents and Systemic Levels of Inflammatory Cytokines in Vulnerable and Stable Atherosclerotic Carotid Plaques. Ann Vasc Surg. 2021 Dec 11:S0890-5096(21)00912-2. doi: 10.1016/j.avsg.2021.10.070. Epub ahead of print. PMID: 34902464.

Locci S, Cardani R, Brunori P, Lucchiari S, Comi GP, Federico A, De Stefano N, Meola G, Mignarri A. Co-occurrence of DMPK expansion and CLCN1 mutation in a patient with myotonia. Neurol Sci. 2021 Dec;42(12):5365-5368. doi: 10.1007/s10072-021-05538-y. Epub 2021 Aug 13. PMID: 34386887.

Cavalli M, Cardani R, Renna LV, Toffetti M, Villa L, Meola G. First Family of MATR3-Related Distal Myopathy From Italy: The Role of Muscle Biopsy in the Diagnosis and Characterization of a Still Poorly Understood Disease. Front Neurol. 2021 Oct 1;12:715386. doi: 10.3389/fneur.2021.715386. PMID: 34659085;PMCID: PMC8517147.

Botta A, Visconti VV, Fontana L, Bisceglia P, Bengala M, Massa R, Bagni I, Cardani R, Sangiuolo F, Meola G, Antonini G, Petrucci A, Pegoraro E, D’Apice MR, Novelli G. A 14-Year Italian Experience in DM2 Genetic Testing: Frequency and Distribution of Normal and Premutated CNBP Alleles. Front Genet. 2021 Jun 21;12:668094. doi: 10.3389/fgene.2021.668094. PMID: 34234810; PMCID: PMC8255792.

Sitzia C, Pistelli L, Cardani R, Renna LV, Ranucci M, Carrara M, Borlini S, Clerici P, Rampoldi B, Cornetta M, Corsi-Romanelli M. Sensitivity of serology assay in Covid-19 diagnosis: does the antigen matter? J Biol Regul Homeost Agents. 2021 May-Jun;35(3):881-887. doi: 10.23812/21-163-A. PMID: 34231353.

Dozio E, Sitzia C, Pistelli L, Cardani R, Rigolini R, Ranucci M, Corsi Romanelli MM. Soluble Receptor for Advanced Glycation End Products and Its Forms in COVID-19 Patients with and without Diabetes Mellitus: A Pilot Study on Their Role as Disease Biomarkers. J Clin Med. 2020 Nov 23;9(11):3785. doi:10.3390/jcm9113785. PMID: 33238596; PMCID: PMC7700384.

Cardani R, Bertoldo EG, Cerri A, Picozzi M, Corsi Romanelli MM, Callus E. Establishment of a cardiac biobank in a Department of Pathology and Laboratory Medicine. J Biol Regul Homeost Agents. 2020 Nov-Dec;34(6):1983-1991. doi: 10.23812/20-158-R. PMID: 33426856.

Ranucci M, Sitzia C, Baryshnikova E, Di Dedda U, Cardani R, Martelli F, Corsi Romanelli M. Covid-19-Associated Coagulopathy: Biomarkers of Thrombin Generation and Fibrinolysis Leading the Outcome. J Clin Med. 2020 Oct 28;9(11):3487. doi: 10.3390/jcm9113487. PMID: 33126772; PMCID: PMC7692774.

Alì M, Monti CB, Melazzini L, Cardani R, Fossati B, Cavalli M, Chow K, Secchi F, Meola G, Sardanelli F. Rare Disease: Cardiac Risk Assessment With MRI in Patients With Myotonic Dystrophy Type 1. Front Neurol. 2020 Mar 19;11:192. doi: 10.3389/fneur.2020.00192. PMID: 32265828; PMCID: PMC7098463.